European Journal of Cardio-thoracic Surgery 29S (2006)
S75-S97
Buckberg GD, Castellá M, Gharib M, Saleh S.
Objective
To study the sequential shortening of Torrent-Guasp’s ‘rope-heart model’ of the muscular band, and analyse the structure—function relationship of basal loop wrapping the outer right and left ventricles, around the inner helical apical loop containing reciprocal descending and ascending spiral segments.
Methods
In 24 pigs (27—82 kg), temporal shortening by sonomicrometer crystals was recorded. The ECG evaluated rhythm, and Millar pressure transducers measured intraventricular pressure and dP/dt.
Results
The predominant shortening sequence proceeded from right to left in basal loop, then down the descending and up the ascending apical loop segments. In muscle surrounded by the basal loop, epicardial muscle predominantly shortened before endocardial muscle. Crystal location defined underlying contractile trajectory; transverse in basal versus oblique in apical loop, subendocardial in descending and subepicardial in ascending segments. Mean shortening fraction average 18 ± 3%, with endocardial exceeding epicardial shortening by 5 ± 1%. Ascending segment crystal displacement followed descending shortening by 82 ± 23ms, and finished 92 ± 33 ms after descending shortening stops, causing active systolic shortening to suction venous return; isovolumetric relaxation was absent.
Conclusion
Shortening sequence followed the rope-like myocardial band model to contradict traditional thinking. Epicardial muscle shortened before endocardial papillary muscle despite early endocardial activation, and suction filling follows active systolic unopposed ascending segment shortening during the ‘isovolumetric relaxation’ phase.
European Journal of Cardio-thoracic Surgery 29S (2006) S75-S97
Buckberg GD, Castellá M, Gharib M, Saleh S.
Objective
To study the sequential shortening of Torrent-Guasp’s ‘rope-heart model’ of the muscular band, and analyse the structure—function relationship of basal loop wrapping the outer right and left ventricles, around the inner helical apical loop containing reciprocal descending and ascending spiral segments.
(more…)
Int Angiol. 2004 Sep;23(3):276-83.
Stonebridge PA, Buckley C, Thompson A, Dick J, Hunter G, Chudek JA, Houston JG, Belch JJ.
Vascular Diseases Research Unit, Department of Surgery, The Institute of Cardiovascular Research, Ninewells Hospital and Medical School, Dundee, Scotland, UK. p.a.stonebridge@dundee.ac.uk
Aim
Physiological blood flow patterns are themselves poorly understood despite their impact on arterial disease. Stable spiral (helical) laminar flow has been observed in normal subjects. (more…)
Frontier Perspectives, J Centre Frontier Sciences, Temple University, Philadelphia, Pa.
1995:Vol 5(1)
Marinelli R, Fuerst B, Zee H, McGinn A, Marinelli W
In 1932, Bremer of Harvard filmed the blood in the very early embryo circulating in self-propelled mode in spiralling streams before the heart was functioning. (more…)
Presented at the Vascular Access for Haemodialysis XIII Symposium, May 9-11, 2012, Orlando, Florida, USA
Nick G. Inston, MD, Yazin Marie, Stephen J. Mallor, Hari Krishnan and Robert Jones
Objectives
In healthy individuals arterial blood flow has been characterized as having a spiral laminar pattern (Stonebridge P et al 1991). A loss of this pattern of flow is associated with pathology (Houston G et al 2004). (more…)
Poster at the Vascular Access Society of Britain and Ireland Symposium, September 2011, Brighton, UK
Guthrie, Suttie, Ross, Levison & Stonebridge
Purpose
In non-atherosclerotic vessels, flow is predominantly ‘spiral laminar’ rather than laminar. Spiral Laminar Flow (SLF) stabilises flow patterns at regions of arterial branching. (more…)
Methodist Debakey Cardiovasc J. 2011 Jan-Mar;7(1):21-6.
Stonebridge P.
Recent work in cardiac and peripheral vascular blood flow has shown evidence for an elegant complexity to flow within the heart and in the large to medium arteries. (more…)
Nephrol Dial Transplant. 2004 Jul;19(7):1786-91. Epub 2004 May 25
Houston JG, Gandy SJ, Milne W, Dick JB, Belch JJ, Stonebridge PA.
Tayside University Hospitals, Clinical Radiology, Dundee, UK. graeme.houston@tuht.scot.nhs.uk
Background
Spiral or helical arterial blood flow patterns have been widely observed in both animals and humans. The absence of spiral flow has been associated with carotid arterial disease. (more…)
J Magn Reson Imaging. 2003 Aug;18(2):169-74.
Houston JG, Gandy SJ, Sheppard DG, Dick JB, Belch JJ, Stonebridge PA.
Department of Clinical Radiology, Ninewells Hospital and Medical School, Tayside University Hospitals NHS Trust, Dundee, Scotland, UK. graemeh@tuht.scot.nhs.uk
Purpose
To determine the effect of age, sex, and presence of carotid atheromatous disease on the presence of aortic spiral blood flow pattern using two-dimensional flow quantitative magnetic resonance imaging (MRI).
(more…)
J Magn Reson Imaging. 1999 Nov;10(5):861-9.
Bogren HG, Buonocore MH.
Abstract
Four-dimensional magnetic resonance MR velocity mapping was developed to study normal flow patterns in the thoracic aorta using time-resolved cardiac gated three-directional velocity data. (more…)
